Utke G, Quos A, Wegener R
Zentralbl Chir. 1980;105(23):1573-82.
Malignant hypothermia seems to depend on a latent hereditary disposition, in the couse of which a defect in the storage of calcium at the cell membrane of the skeletal - and heart muscle happens. The aetiology of the disease could not be fully explained until now. The mechanism is especially triggered by medicaments in routine anaesthesiological use. There is no preanaesthesiologic method to detect persons prone to malignant hypothermia. 3 cases of this kind are dealt with in detail. All 3 patients came to death although the measures of treatment taken immediately corresponded completely to the present state of knowledge.
恶性高热似乎取决于一种潜在的遗传倾向，在此过程中，骨骼肌和心肌细胞膜上的钙储存出现缺陷。迄今为止，该病的病因尚不能完全解释清楚。其机制尤其由常规麻醉中使用的药物引发。目前尚无麻醉前检测易患恶性高热者的方法。详细介绍了3例此类病例。尽管立即采取的治疗措施完全符合目前的认知水平，但所有3例患者均死亡。
