Atterhög J H
Acta Med Scand. 1981;209(1-2):75-82. doi: 10.1111/j.0954-6820.1981.tb11555.x.
Forty-eight subjects (group T) with primary T wave aberrations in their electrocardiograms (e.g. notches, flattening or inversion in leads II, CR4 and CR7 but without a concomitant ST depression) and 38 controls (group C), examined previously at the age of 18-19 years, were re-examined after 5.4 and 7.5 years respectively. The incidence of heart disease between the two examinations was lower in group T than in the controls. The T wave aberration had decreased in severity in 22 subjects in group T, but 66% of them still showed T wave aberrations at rest. Only one subject was free from T wave aberrations during orthostasis. Beta-adrenergic blockade in 27 subjects in group T suggested that 3 possibly had organic genesis to the aberrations. The earlier reported signs of high sympathetic tone in group T had decreased, but a somewhat higher heart rate and diastolic blood pressure than in the controls still remained. The systolic time intervals suggested larger stroke volumes in group T than in the controls and did not indicate decreased myocardial performance in group T. The attenuated differences between groups T and C in T wave abnormality, heart rate and blood pressure over the follow-up period suggest that T wave abnormality as an isolated finding in young men is a benign finding.
48名心电图有原发性T波异常（如II导联、CR4导联和CR7导联出现切迹、低平或倒置，但无伴随的ST段压低）的受试者（T组）和38名对照者（C组），他们曾在18 - 19岁时接受过检查，分别在5.4年和7.5年后再次接受检查。两次检查之间，T组心脏病的发病率低于对照组。T组中有22名受试者的T波异常严重程度有所减轻，但其中66%的人在静息时仍有T波异常。只有1名受试者在直立位时无T波异常。对T组中的27名受试者进行β - 肾上腺素能阻滞剂试验表明，其中3人可能存在器质性T波异常。之前报道的T组高交感神经张力迹象有所减轻，但仍比对照组略高的心率和舒张压依然存在。收缩期时间间期表明，T组的每搏输出量比对照组大，且未提示T组心肌功能下降。在随访期间，T组和C组在T波异常、心率和血压方面的差异减弱，这表明在年轻男性中孤立出现的T波异常是一种良性表现。
