May K L
Allergol Immunopathol (Madr). 1980 Nov-Dec;8(6):643-50.
From a representative group from the adult population (34.958) of a town of 77.384 inhabitants, 99 persons were selected who: a) claimed to be periodically dyspneic independently with respect to respiratory tract infections. b) had normal chest x-rays and normal PE flow values. Approximately one year later, a history of atopic diseases was taken from 79 of them, and intradermal skin tests were performed with some inhalants and food allergens. At this time, 15 persons failed to report their previous complaints of dyspnea. Only 5 persons reported that various vegetables and pickles were responsible for their urticaria or eczema. Only 2 persons admitted various gastrointestinal symptoms, but non mentioned milk, eggs or cereals as possible causative agents of their bronchial, nasal, skin or circulatory symptoms. Distinctly positive immediate type skin reactions to the mixed milk and egg allergen were recorded in 19 patients (24%), and to cereals in 11 persons (14%). They all reacted strongly also to the house dust allergen, but they did not differ from all the remaining subjects in the intensity of their skin response to the control solution of histamine. People with positive skin reactions to cereals or dairy products complained of chronic or recurrent rhinitis much more often than the others (73% and 63% compared with 35%). Forty-five (47%) of them had a positive personal history of urticaria or eczema. These "food reactors" did not differ from "non reactors" in the frequency of the elevated serum IgE level which was raised in 66% of the whole group (of 79). The results suggest that allergy to cereals and dairy products may often be underestimated in adult asthmatics especially when positive reactions to inhalants are also present. The problems of reliability of the skin tests and history taking in food allergy are briefly discussed.
从一个有77384名居民的城镇的成年人群体（34958人）中选取了99人，这些人：a）声称与呼吸道感染无关，会周期性地出现呼吸困难。b）胸部X光检查正常，肺功能流量值正常。大约一年后，对其中79人进行了特应性疾病史调查，并对一些吸入性过敏原和食物过敏原进行了皮内皮肤试验。此时，有15人未报告他们之前的呼吸困难症状。只有5人报告各种蔬菜和泡菜是他们荨麻疹或湿疹的病因。只有2人承认有各种胃肠道症状，但没有人提到牛奶、鸡蛋或谷物是他们支气管、鼻腔、皮肤或循环系统症状的可能病因。19名患者（24%）对混合牛奶和鸡蛋过敏原的速发型皮肤反应呈明显阳性，11人（14%）对谷物呈阳性反应。他们对屋尘过敏原也都有强烈反应，但在对组胺对照溶液的皮肤反应强度上，他们与所有其他受试者没有差异。对谷物或乳制品皮肤反应呈阳性的人比其他人更常抱怨慢性或复发性鼻炎（分别为73%和63%，而其他人是35%）。其中45人（47%）有荨麻疹或湿疹的个人阳性病史。这些“食物反应者”与“非反应者”在血清IgE水平升高的频率上没有差异，在整个79人的群体中，66%的人血清IgE水平升高。结果表明，在成年哮喘患者中，对谷物和乳制品的过敏可能常常被低估，尤其是当对吸入性过敏原也呈阳性反应时。文中简要讨论了食物过敏中皮肤试验和病史采集的可靠性问题。
