Hecht H S, Hopkins J M
Am J Cardiol. 1981 Apr;47(4):861-5. doi: 10.1016/0002-9149(81)90186-7.
Exercise-induced regional wall motion abnormalities on radionuclide angiography have been thought to be a reliable indicator of coronary artery disease. To evaluate their reliability, particularly in patients with valvular heart disease, exercise radionuclide angiography was performed in 12 normal subjects, 35 patients with coronary artery disease and 19 patients with valvular heart disease and normal coronary arteries. Exercise-induced regional wall motion abnormalities were found in none of the normal subjects, 63 percent of the patients with coronary artery disease and 42 percent of those with valvular heart disease and were predominantly inferoapical in location in the group with valvular heart disease. We conclude that exercise-induced regional wall motion abnormalities are not reliable for the detection of coronary artery disease in patients with valvular heart disease.
放射性核素血管造影术中运动诱发的局部室壁运动异常一直被认为是冠状动脉疾病的可靠指标。为评估其可靠性，尤其是在瓣膜性心脏病患者中的可靠性，对12名正常受试者、35名冠状动脉疾病患者和19名瓣膜性心脏病且冠状动脉正常的患者进行了运动放射性核素血管造影检查。正常受试者中均未发现运动诱发的局部室壁运动异常，冠状动脉疾病患者中有63%出现该异常，瓣膜性心脏病患者中有42%出现该异常，且在瓣膜性心脏病组中主要位于下壁心尖部。我们得出结论，运动诱发的局部室壁运动异常对于检测瓣膜性心脏病患者的冠状动脉疾病并不可靠。
