Goske J, Askari A D, Dickman E, Forman W B, Crum E D
Am J Hematol. 1980;9(4):435-7. doi: 10.1002/ajh.2830090411.
Sjogren syndrome is a multi-system disease leading to diverse organ involvement during its course [1, 2]. Hematologic abnormalities described in Sjogren syndrome include anemia, mild leukopenia [3, 4], eosinophilia, elevated erythrocyte sedimentation rate, hypergammaglobulinemia, mixed cryoglobulinemia, and a variety of autoantibodies [5]. Marked lymphocytosis with granulocytopenia is distinctly unusual and has not been previously reported. We report a case of Sjogren syndrome who presented with constellation of the latter problems without prominent sicca manifestations.
干燥综合征是一种多系统疾病，在其病程中可导致多种器官受累[1,2]。干燥综合征中描述的血液学异常包括贫血、轻度白细胞减少[3,4]、嗜酸性粒细胞增多、红细胞沉降率升高、高球蛋白血症、混合性冷球蛋白血症以及多种自身抗体[5]。显著淋巴细胞增多伴粒细胞减少极为罕见，此前未见报道。我们报告一例干燥综合征患者，其表现为上述一系列问题，但无明显的口干眼干症状。
