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葡萄糖酸钙与美索巴莫(罗巴克辛)治疗黑寡妇蜘蛛咬伤的疗效比较

A comparison of calcium gluconate and methocarbamol (Robaxin) in the treatment of Latrodectism (black widow spider envenomation).

作者信息

Key G F

出版信息

Am J Trop Med Hyg. 1981 Jan;30(1):273-7. doi: 10.4269/ajtmh.1981.30.273.

DOI:10.4269/ajtmh.1981.30.273
PMID:7212170
Abstract

Calcium gluconate and methocarbamol were compared by using an algorithmic treatment protocol on all cases of Latrodectus (black widow) envenomation seen over a period of 3 years. Six of 13 patients were effectively cured of their symptoms by calcium gluconate, while only one of 10 patients was relieved by methocarbamol. Calcium gluconate remains the drug of first choice for this syndrome. It was also noted that calcium gluconate was more effective in patients who presented 3 hours of more after they were bitten. Antivenom may be necessary in those who present with symptoms in less than 3 hours.

摘要

在3年期间对所有黑寡妇蜘蛛咬伤病例采用一种算法治疗方案,比较了葡萄糖酸钙和甲氯芬那酸的疗效。13例患者中有6例通过葡萄糖酸钙有效治愈症状,而10例患者中只有1例通过甲氯芬那酸缓解症状。葡萄糖酸钙仍然是该综合征的首选药物。还注意到,葡萄糖酸钙对咬伤后3小时或更长时间出现症状的患者更有效。对于咬伤后不到3小时出现症状的患者,可能需要使用抗蛇毒血清。

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