Zieger G, Breuner H, Kubatsch B
Anat Anz. 1980;148(2):115-23.
Earlier studies showed a sex dimorphism of the adrenal cortex of the hamster developing during puberty. Morphologically, this is most evident in the zone reticularis. The male has larger reticular cells than the female, 60 pairs of siblings were castrated around the 10th day of life; 6 males and females were sacrificed at weekly intervals between the 3rd and 12th week of life. 60 pairs of uncastrated siblings served as control. Till the 10th week of life the body and adrenal weight of the castrated males agree with those of the castrated females. From the 11th week onwards the males have the higher body and adrenal weight. Neither histometrically nor histologically there are differences in the adrenal structure of the 2 castrated sexes. Both groups have small reticular cells. Compared to the uncastrated animal the male castrated hamster has a higher body and a lower adrenal weight, whereas the female castrate shows no significant difference in comparison with the non-castrate of the same age and sex. Thus, the adrenal cortex of the Syrian golden hamster is stimulated by androgen hormone. This result is contrary to the rat adrenal, where changes, caused by gonadectomy, are found in the female, and the female adrenal is stimulated by estrogen.
早期研究表明，仓鼠肾上腺皮质在青春期发育过程中存在性别二态性。从形态学上看，这在网状带最为明显。雄性的网状细胞比雌性大。60对同胞仓鼠在出生后第10天左右被阉割；在出生后第3周和第12周之间，每周处死6只雄性和雌性仓鼠。60对未阉割的同胞仓鼠作为对照。直到出生后第10周，阉割雄性仓鼠的体重和肾上腺重量与阉割雌性仓鼠的一致。从第11周起，雄性仓鼠的体重和肾上腺重量更高。在组织计量学和组织学上，两种阉割性别的肾上腺结构均无差异。两组都有小的网状细胞。与未阉割动物相比，雄性阉割仓鼠体重较高而肾上腺重量较低，而雌性阉割仓鼠与同龄同性别未阉割仓鼠相比无显著差异。因此，叙利亚金仓鼠的肾上腺皮质受到雄激素的刺激。这一结果与大鼠肾上腺相反，在大鼠中，性腺切除引起的变化见于雌性，且雌性肾上腺受到雌激素的刺激。
