Linker C A, Newcom S R, Nilsson C M, Wolf J L, Shuman M A
Ann Intern Med. 1980 Nov;93(5):704-7. doi: 10.7326/0003-4819-93-5-704.
We report a case of combined idiopathic immune neutropenia and immune thrombocytopenia (thromboneutropenia). Therapy with prednisone was ineffective. Treatment with vincristine raised the patient's platelet count but did not increase the neutrophil count. Splenectomy led to a prompt complete remission. Using radioimmunologic techniques, we have shown both antiplatelet and antineutrophil antibodies and have shown the disappearance of these antibodies after successful treatment.
我们报告了一例合并特发性免疫性中性粒细胞减少症和免疫性血小板减少症（血栓性中性粒细胞减少症）的病例。泼尼松治疗无效。长春新碱治疗使患者血小板计数升高，但未增加中性粒细胞计数。脾切除术后迅速完全缓解。运用放射免疫技术，我们检测到了抗血小板和抗中性粒细胞抗体，并发现成功治疗后这些抗体消失。
