Srivastava K, Das Gupta P K, Mehrotra P K
Indian J Physiol Pharmacol. 1978 Jul-Sep;22(3):310-2.
Monoamine oxidase activity (MAO) was estimated in the pituitary of ovariectomized mice after a single administration of estradiol-dipropionate (0.01 mg/kg; im), progesterone (1 mg/kg; im) and centchroman (1.25 mg/kg ip). Estrogen and progesterone were found to decrease the enzymic level, as compared to control, while centchroman remarkably increased it. The significance of dissimilarity in the pituitary threshold for steroidal and nonsteroidal molecule is discussed.
在切除卵巢的小鼠垂体中，测定了单次注射二丙酸雌二醇（0.01mg/kg；腹腔注射）、孕酮（1mg/kg；腹腔注射）和醋炔诺酮（1.25mg/kg 腹腔注射）后单胺氧化酶活性（MAO）。与对照组相比，发现雌激素和孕酮会降低酶水平，而醋炔诺酮则显著提高酶水平。讨论了甾体和非甾体分子在垂体阈值方面差异的意义。
