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Stimulation of human NK-cell activity by cultured cells. I. Response of normals.

作者信息

Grohmann P, Holmes W, Porzsolt F, Quirt I, Miller R G, Phillips R A

出版信息

Int J Cancer. 1978 Nov 15;22(5):528-34. doi: 10.1002/ijc.2910220504.

Abstract

Natural cell-mediated cytotoxicity, observed on co-cultivation of peripheral blood lymphocytes (PBL) with malignant melanoma tumor cells (M4), is described. The activity was inhibited when PBL were cultured in autologous serum. Studies using competitive inhibition with cold targets and stimulation of PBL with other tumor cell lines failed to detect specificity.

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