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Stimulation of human NK-cell activity by cultured cells. I. Response of normals.

作者信息

Grohmann P, Holmes W, Porzsolt F, Quirt I, Miller R G, Phillips R A

出版信息

Int J Cancer. 1978 Nov 15;22(5):528-34. doi: 10.1002/ijc.2910220504.

DOI:10.1002/ijc.2910220504
PMID:721315
Abstract

Natural cell-mediated cytotoxicity, observed on co-cultivation of peripheral blood lymphocytes (PBL) with malignant melanoma tumor cells (M4), is described. The activity was inhibited when PBL were cultured in autologous serum. Studies using competitive inhibition with cold targets and stimulation of PBL with other tumor cell lines failed to detect specificity.

摘要

相似文献

1
Stimulation of human NK-cell activity by cultured cells. I. Response of normals.
Int J Cancer. 1978 Nov 15;22(5):528-34. doi: 10.1002/ijc.2910220504.
2
In vitro cytotoxicity and transplantation protection by autologous natural and activated killer cells against an in vitro transformed tumorigenic fibroblast line. A case study.自体天然杀伤细胞和活化杀伤细胞对体外转化的致瘤性成纤维细胞系的体外细胞毒性及移植保护作用。一项病例研究。
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VLA-6 (CDw49f) is an important adhesion molecule in NK cell-mediated cytotoxicity following autologous or allogeneic bone marrow transplantation.VLA - 6（CDw49f）是自体或异基因骨髓移植后自然杀伤细胞介导的细胞毒性中的一种重要黏附分子。
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Nat Immun Cell Growth Regul. 1985;4(6):315-27.

引用本文的文献

1
Stimulation of human NK cell activity by cultured cells. II Ingestion of aspirin by blood donors suppresses induced NK activity.培养细胞对人自然杀伤细胞活性的刺激。II. 献血者服用阿司匹林会抑制诱导的自然杀伤细胞活性。
Clin Exp Immunol. 1981 Jun;44(3):611-4.
2
Deficient natural killer cell activity in a patient with Fanconi's anaemia and squamous cell carcinoma. Association with defect in interferon release.范可尼贫血合并鳞状细胞癌患者自然杀伤细胞活性缺乏。与干扰素释放缺陷相关。
Clin Exp Immunol. 1982 Apr;48(1):205-12.