Battmer R D, Lehnhardt E
Arch Otorhinolaryngol. 1981;230(1):37-47. doi: 10.1007/BF00665378.
The component P6 of the brain stem is only to be related to the hearing ability in the high tone range of greater than or equal to 2 kHZ, but it can be traced up to the hearing threshold. The cortex response N90, on the other hand, is frequency-specific, but it can hardly be recorded up to the subjective hearing threshold. The slow brain stem response SN10 (Davis and Hirsh 1979), unaffected by medicamented sleep, shall give information about hearing ability in the low and medium frequency range and may thus be an ideal complement to the fast response P6. In a number of normal hearing people and patients with sensorial hearing impairment of different frequency characteristics the brain stem responses P6 and SN10 were simultaneously recorded. As stimuli we used tone pips of a rise and fall time independent of frequency of about 2 ms and with a plateau of 2 ms as well. The mean threshold of the SN10 response is about 10 dB above the subjective hearing threshold. The constancy of the latencies corresponds to that of P6. The frequency selectivity of this relatively slow brain stem response is proved by comparing the P6 and SN10 responses with the course of the subjective hearing threshold. The topodiagnostic significance of the wave SN10 in connection with the brain stem response P6 and the cortical response N90 is shown in a case of neural hearing impairment.
脑干的P6成分仅与大于或等于2千赫兹的高音调范围内的听力相关，但它可以追溯到听力阈值。另一方面，皮层反应N90具有频率特异性，但很难记录到主观听力阈值。不受药物诱导睡眠影响的脑干慢反应SN10（戴维斯和赫什，1979年）应能提供关于中低频范围内听力的信息，因此可能是快速反应P6的理想补充。在一些听力正常的人和具有不同频率特征的感觉神经性听力障碍患者中，同时记录了脑干反应P6和SN10。作为刺激，我们使用了上升和下降时间与频率无关、约为2毫秒且平台期也为2毫秒的短音。SN10反应的平均阈值比主观听力阈值高约10分贝。潜伏期的稳定性与P6的稳定性相当。通过将P6和SN10反应与主观听力阈值的过程进行比较，证明了这种相对较慢的脑干反应的频率选择性。在一例神经性听力障碍病例中，显示了波SN10与脑干反应P6和皮层反应N90相关的定位诊断意义。
