Tarquini A, di Martino L, Malloci A, Kwa H G, van der Gugten A A, Bulbrook R D, Wang D Y
Int J Cancer. 1978 Dec;22(6):687-90. doi: 10.1002/ijc.2910220608.
In the present study the assay results of prolactin concentrations in serial samples of blood obtained from premenopausal women with benign or malignant disease of the breast are compared with--and discussed in relation to--findings reported in earlier studies based on single samples of blood taken at various times from a large and ostensibly normal population of women. The finding of an abnormality in nycthemeral prolactin levels in the established disease is considered to strengthen the concept that the same abnormality found in high-risk groups is of aetiological importance.
在本研究中，对从患有良性或恶性乳腺疾病的绝经前女性采集的系列血样中催乳素浓度的检测结果，与早期基于从大量表面正常的女性群体在不同时间采集的单份血样所报告的研究结果进行了比较，并展开了相关讨论。已确诊疾病患者昼夜催乳素水平异常这一发现，被认为强化了以下观念：在高危人群中发现的同样异常具有病因学意义。
