Weihl A C, Langworthy H C, Manalaysay A R, Layton R P
Aviat Space Environ Med. 1981 Feb;52(2):88-91.
This study was undertaken to determine the hormonal responses to disabling hypothermia as a result of cold water immersion. Thermally unprotected male divers trained by the U.S. Navy were subjected to total body immersion in water at 25.5 degrees C and 33 degrees C. Plasma epinephrine, norepinephrine, growth hormone, and cortisol were measured. Other variables monitored included oxygen consumption, carbon dioxide production, minute ventilation, and rectal temperature. Immersion without cold stress caused suppression of plasma epinephrine without affecting plasma norepinephrine. Cold stress combined with immersion caused a significant increase in plasma norepinephrine in the absence of other indicators of a generalized stress reaction. The degree of chilling seen in this study will produce disabling hypothermia within 1-2 h and may be shown initially only by an increase in plasma norepinephrine.
本研究旨在确定因冷水浸泡导致失能性体温过低时的激素反应。接受美国海军训练的未采取热防护措施的男性潜水员全身浸入25.5摄氏度和33摄氏度的水中。测量了血浆肾上腺素、去甲肾上腺素、生长激素和皮质醇。监测的其他变量包括耗氧量、二氧化碳生成量、分钟通气量和直肠温度。无冷应激的浸泡导致血浆肾上腺素受到抑制,而血浆去甲肾上腺素未受影响。冷应激与浸泡相结合,在无全身性应激反应的其他指标的情况下,导致血浆去甲肾上腺素显著增加。本研究中观察到的寒冷程度将在1-2小时内导致失能性体温过低,最初可能仅表现为血浆去甲肾上腺素升高。