Chiara O, Clement M G, Lazzaroni A, Triulzi M O
Boll Soc Ital Biol Sper. 1980 Nov 15;56(21):2228-33.
The hemodynamic effects of a synthetic compound of PGF 2 alpha have been studied before and after vagosympathectomy. Synthetic PGF 2 alpha caused a marked hypertension in the pulmonary circulation linked with the vasoconstrictor action of this substance on the small lung vessels. A slight hypotension was observed in the denervated animal where the highest values of pulmonary pressure were reached. The authors conclude that this fact may be due to an inhibition of the vasoconstrictor systemic tone secondary to the pulmonary hypertensive state.
在迷走神经交感神经切除术前和术后，对一种合成的前列腺素F2α化合物的血流动力学效应进行了研究。合成的前列腺素F2α在肺循环中引起显著的高血压，这与该物质对肺小血管的血管收缩作用有关。在去神经支配的动物中观察到轻微的低血压，其肺压达到最高值。作者得出结论，这一事实可能是由于肺高血压状态继发的血管收缩性全身张力受到抑制。
