Srinivasan C N, Misra U K
Biochem Exp Biol. 1980;16(1):67-76.
Effect of partial hepatectomy and administration of actinomycin D to partially hepatectomized dogs was studied on the amounts of serum and betalipoprotein phospholipids and incorporation of NaH2 32PO4 into various phospholipid at various periods after surgery. Partial hepatectomy generally did not affect the amounts of various phospholipids as compared to the sham operated controls, though the values in experimental dogs were lower than the control. Actinomycin D did not affect serum and betalipoprotein phospholipids as compared to the sham operated controls. Partial hepatectomy reduced the incorporation of NaH2 32PO4 into all phospholipid components of serum and betalipoprotein as compared to sham operated controls. However, administration of actinomycin D to partially hepatectomized dogs stimulated the incorporation of NaH2 32PO4 into all serum and betalipoprotein phospholipid components, being more prominent in the case of lysophosphatidyl-choline as compared to the partially hepatectomized dogs.
研究了部分肝切除以及对部分肝切除的犬给予放线菌素D，对术后不同时期血清和β脂蛋白磷脂含量以及NaH2 32PO4掺入各种磷脂的影响。与假手术对照组相比，部分肝切除一般不影响各种磷脂的含量，尽管实验犬的值低于对照组。与假手术对照组相比，放线菌素D不影响血清和β脂蛋白磷脂。与假手术对照组相比，部分肝切除减少了NaH2 32PO4掺入血清和β脂蛋白的所有磷脂成分。然而，对部分肝切除的犬给予放线菌素D刺激了NaH2 32PO4掺入所有血清和β脂蛋白磷脂成分，与部分肝切除的犬相比，溶血磷脂酰胆碱的情况更明显。
