Srinivasan C N, Misra U K
Biochem Exp Biol. 1980;16(1):77-86.
Effect of administration of actinomycin D to partially hepatectomized dogs has been studied on various neutral and phospholipid components of serum and its beta-lipoprotein fraction. Partial hepatectomy altered distribution of palmitic, stearic, oleic, linoleic and arachidonic acid in various components of neutral lipids and phospholipids of serum and its dextran sulphate precipitable fraction. Administration of actinomycin D to partially hepatectomized dogs reduced the levels of stearic acid and linoleic acid and increased that of oleic acid in triglyceride component; reduced the levels of oleic and linoleic acids in esterified cholesterol; raised the levels of stearic acid of phosphatidyl choline and reduced the levels of linoleic and palmitic acid of lysophosphatidyl choline.
已经研究了对部分肝切除的狗施用放线菌素D对血清及其β-脂蛋白组分的各种中性和磷脂成分的影响。部分肝切除术改变了血清及其硫酸葡聚糖可沉淀组分的中性脂质和磷脂的各种成分中棕榈酸、硬脂酸、油酸、亚油酸和花生四烯酸的分布。对部分肝切除的狗施用放线菌素D降低了甘油三酯组分中硬脂酸和亚油酸的水平，并增加了油酸的水平；降低了酯化胆固醇中油酸和亚油酸的水平；提高了磷脂酰胆碱的硬脂酸水平，并降低了溶血磷脂酰胆碱的亚油酸和棕榈酸水平。
