Ralfs I G, Dawber R P, Ryan T J, Wright N A
Br J Dermatol. 1981 Mar;104(3):249-52. doi: 10.1111/j.1365-2133.1981.tb00945.x.
Epidermal proliferative kinetics were studied in a patient with pityriasis rubra pilaris. Elevated proliferative indices (flash labelling and mitotic indices) were apparent compared with normal epidermis and measurements of the birth rate indicate that the rate of epidermal cell production was similar to that found in psoriasis, and equalled 11.8 cells/1000 germinative cells/h; this suggests a cell cycle time of 60 h. Contemporaneous measurements of the rate of entry into DNA synthesis showed values similar to the rate of entry into mitosis; hence there is no G2 cell loss as appears to occur in the hyperproliferative psoriatic epidermis.
对一名毛发红糠疹患者的表皮增殖动力学进行了研究。与正常表皮相比，增殖指数（闪烁标记和有丝分裂指数）明显升高，并且出生率的测量表明表皮细胞产生速率与银屑病中的相似，等于11.8个细胞/1000个生发细胞/小时；这表明细胞周期时间为60小时。同时对进入DNA合成速率的测量显示其值与进入有丝分裂的速率相似；因此，不存在像银屑病增生性表皮中那样的G2期细胞丢失。
