Simionescu C I, Dénes F, Totolin M
Biosystems. 1981;13(3):149-156. doi: 10.1016/0303-2647(81)90056-3.
Starting from a simple gas mixture rich in methane, suggested as being a model of the primeval atmosphere for a certain time period, we succeeded in synthesizing lipid-like compounds. The hydrophobic nature of the products was demonstrated by IR, NMR, MS, elementary analysis, gel filtration measurements and solubility tests. The hydrophobic products self-assemble in stable, uniformly sized microspheres possessing membrane-like properties. They can selectively retain biologically active compounds. The wall-membrane of the microspheres shows a supramolecular order.
从一种富含甲烷的简单气体混合物出发（该混合物被认为在某一时期是原始大气的模型），我们成功合成了类脂化合物。通过红外光谱（IR）、核磁共振（NMR）、质谱（MS）、元素分析、凝胶过滤测量和溶解度测试证明了产物的疏水性。这些疏水性产物能自组装成具有膜状性质的稳定、尺寸均匀的微球。它们能选择性地保留生物活性化合物。微球的壁膜呈现出超分子有序结构。
