[论甲状腺癌的治疗（作者译）]

[On the treatment of carcinoma of the thyroid (author's transl)].

作者信息

Biersack H J, Vogt M, Helpap B, Janson R, Rau W, Winkler C

出版信息

Dtsch Med Wochenschr. 1981 Mar 27;106(13):390-5. doi: 10.1055/s-2008-1070323.

DOI:10.1055/s-2008-1070323

Abstract

Treatment of carcinoma of the thyroid includes, in addition to possible total surgical removal of thyroid and tumour tissue, obligatory radio-iodine treatment as well as administration of thyroid hormone in high dosage. Patients with anaplastic carcinoma as well as those with differentiated carcinoma which has broken into vessels or capsule or metastasized, are additionally given percutaneous radiation treatment. Cumulative survival rate for papillary thyroid carcinoma, treated according to this schema, was for women 95% after three years, 83% after five and 53% after ten years. Corresponding survival rates in men were 93%, 78% and 20% respectively. Rates for follicular thyroid carcinoma in women were 87% at three years, 75% at five and 50% at ten years. In men corresponding figures were 94, 77 and 50%. Dividing patients with differentiated thyroid carcinoma (210) into various risk groups, those with papillary and follicular carcinoma manifesting at an age under 45 years had a better prognosis than that after 45 years. Worst prognosis was with anaplastic thyroid carcinoma, when survival rates at one, three and five years were 41, 28 and 18%, respectively.

摘要

甲状腺癌的治疗方法除了可能需要手术彻底切除甲状腺及肿瘤组织外，还包括必须进行放射性碘治疗以及大剂量服用甲状腺激素。对于未分化癌患者以及分化型癌已侵犯血管、包膜或发生转移的患者，还需进行经皮放射治疗。按照这种方案治疗的乳头状甲状腺癌患者，女性三年后的累积生存率为95%，五年后为83%，十年后为53%。男性相应的生存率分别为93%、78%和20%。女性滤泡状甲状腺癌患者三年后的生存率为87%，五年后为75%，十年后为50%。男性的相应数字分别为94%、77%和50%。将分化型甲状腺癌患者（210例）分为不同风险组后发现，年龄在45岁以下的乳头状和滤泡状癌患者的预后比45岁以上患者更好。未分化甲状腺癌的预后最差，其一年、三年和五年的生存率分别为41%、28%和18%。