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The selective effect of tunicamycin on the secretion of IgM and IgG produced by the same cells.

作者信息

Blatt C, Haimovich J

出版信息

Eur J Immunol. 1981 Jan;11(1):65-6. doi: 10.1002/eji.1830110114.

DOI:10.1002/eji.1830110114
PMID:7215424
Abstract

Cells of the hybridoma cell line X63/38 C-13 secreting both IgM and IgG have been used in studies on the importance of the carbohydrate moieties of the Ig molecules for their secretion. It has been found that the secretion of the IgM produced in the presence of the glycosylation inhibitor tunicamycin was strongly inhibited, while the secretion of the IgG produced by the same cells was only slightly affected.

摘要

相似文献

1
The selective effect of tunicamycin on the secretion of IgM and IgG produced by the same cells.
Eur J Immunol. 1981 Jan;11(1):65-6. doi: 10.1002/eji.1830110114.
2
Effect of tunicamycin on IgM, IgA, and IgG secretion by mouse plasmacytoma cells.衣霉素对小鼠浆细胞瘤细胞分泌IgM、IgA和IgG的影响。
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Induction of secretion of IgM from cells of the B cell line 38c-13 by somatic cell hybridization.通过体细胞杂交诱导B细胞系38c - 13细胞分泌IgM
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4
Immunoglobulin production by lymphocyte hybridomas.淋巴细胞杂交瘤产生免疫球蛋白
Eur J Immunol. 1978 Feb;8(2):82-8. doi: 10.1002/eji.1830080203.
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Selective cytotoxicity of purified homologues of tunicamycin on transformed BALB/3T3 fibroblasts.衣霉素纯化同系物对转化的BALB/3T3成纤维细胞的选择性细胞毒性。
Cancer Res. 1983 Feb;43(2):845-50.
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[Tunicamycin inhibition of carbohydrate incorporation into thyroglobulin].
C R Seances Soc Biol Fil. 1981;175(4):446-51.
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Role of glycosylation in the cell surface expression and secretion of immunoglobulin molecules by BCL1 cells.
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Effect of tunicamycin and neuraminidase on the expression of Fc-IgM and -IgG receptors on human lymphocytes.
J Immunol. 1980 Apr;124(4):1830-6.
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Effect of tunicamycin on production by mouse fibroblast L929 cells of the factor-stimulating differentiation of mouse myeloid leukemic cells and the colony-stimulating factor.衣霉素对小鼠成纤维细胞L929细胞产生刺激小鼠髓性白血病细胞分化的因子及集落刺激因子的影响。
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Glycosylation is not required for membrane localization or secretion of IgM in a mouse B cell lymphoma.在小鼠B细胞淋巴瘤中，糖基化对于IgM的膜定位或分泌并非必需。
J Immunol. 1981 May;126(5):1868-73.

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