甘珀酸对慢性萎缩性胃黏膜的影响：通过流式细胞术和组织放射自显影术测定
The effect of carbenoxolone on the chronic atrophic gastric mucosa determined by flow cytometry and histoautoradiography.
作者信息
Weiss H, Steenbeck L, Gütz H J, Wolff G
出版信息
Digestion. 1981;21(3):151-5. doi: 10.1159/000198556.
PMID:7215718
Abstract
A trial with carbenoxolone at a dose of 150 mg/day for 6 months was performed in 24 patients with chronic atrophic gastritis. A control group of 21 patients received placebos. Gastric mucosa was examined by flow cytometry (FC) and histoautoradiography 2, 4, 12 and 24 weeks after starting therapy. Carbenoxolone had neither an effect on cell cycle stage distribution as determined by FC nor on the labelling indices obtained by histoautoradiography.
摘要
对24例慢性萎缩性胃炎患者进行了一项试验，给予羧苄索龙，剂量为150毫克/天，持续6个月。21例患者的对照组接受安慰剂。在开始治疗后的2、4、12和24周，通过流式细胞术（FC）和组织放射自显影检查胃黏膜。羧苄索龙对FC测定的细胞周期阶段分布以及组织放射自显影获得的标记指数均无影响。
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