Walther B, Zönnchen B, Hehlmann R, Schattenkirchner M
Fortschr Med. 1981 Mar 12;99(10):321-5.
In three patients arthropathy was the earliest symptom of hemochromatosis. Two of these patients had a precirrhotic stage of hemochromatosis. The liver histology of the third patient showed a beginning cirrhosis. The serum iron ranged from 212 to 260 micrograms/dl. The transferrin saturation was 95-100%. Serum iron and transferrin should be determined in all patients with arthralgias, since arthropathy may be the first clinical sign of hemochromatosis.
在三名患者中，关节病是血色素沉着症最早出现的症状。其中两名患者处于血色素沉着症的肝硬化前期。第三名患者的肝脏组织学检查显示有早期肝硬化。血清铁含量在212至260微克/分升之间。转铁蛋白饱和度为95%-100%。对于所有有关节痛的患者都应测定血清铁和转铁蛋白，因为关节病可能是血色素沉着症的首个临床体征。
