Pande D N, Nagchaudhuri J
Indian J Physiol Pharmacol. 1980 Oct-Dec;24(4):294-8.
Ketogenic amino acids L-leucine and L-isoleucine were administered in amounts of 100 mg with or without 1.5 g glucose to overnight fasting laying hens. On administering leucine the blood glucose level was observed to be slightly reduced while administration of isolencine increased the blood sugar. On injecting leucine or isoleucine with glucose blood glucose level was found to be appreciably higher as compared to that observed on administering glucose alone. In vivo administration of amino acids caused only a slight increase in plasma alpha-amino nitrogen. The liver glycogen was found to be reduced after the administration of amino acids. these observations indicate that amino acids leucine and isoleucine exercise a definite role on glucose uptake, and its mechanism of utilization in poultry birds is different from mammals.
向过夜禁食的产蛋母鸡分别给予100毫克生酮氨基酸L-亮氨酸和L-异亮氨酸，其中一组同时给予或不给予1.5克葡萄糖。给予亮氨酸后，观察到血糖水平略有降低，而给予异亮氨酸则使血糖升高。与单独给予葡萄糖相比，同时注射亮氨酸或异亮氨酸和葡萄糖时，血糖水平明显更高。体内给予氨基酸仅使血浆α-氨基氮略有增加。给予氨基酸后，肝脏糖原减少。这些观察结果表明，亮氨酸和异亮氨酸对家禽的葡萄糖摄取有明确作用，其利用机制与哺乳动物不同。
