关节腔内注射皮质类固醇和水杨酸盐对关节软骨表面结构的影响。
Effects of intra-articularly administered corticosteroids and salicylates on the surface structure of articular cartilage.
作者信息
Lutfi A M, Kosel K
出版信息
J Anat. 1978 Oct;127(Pt 2):393-402.
Abstract
This study was designed to evaluate the effects of repeated intra-articular corticosteroid and salicylate injections on the surface structure of articular cartilage in the rabbit, using the scanning electron miscroscope. We have shown that the normal surface of the rabbit's articular cartilage presents shallow depressions and mound-like elevations and that corticosteroid-treated articular cartilage exhibits progressive lesions, including fissuring and fraying. The effects of salicylates require further investigation.
摘要
本研究旨在利用扫描电子显微镜评估反复关节内注射皮质类固醇和水杨酸盐对兔关节软骨表面结构的影响。我们已经表明，兔关节软骨的正常表面呈现出浅凹陷和丘状隆起，而经皮质类固醇处理的关节软骨表现出进行性病变，包括裂隙和磨损。水杨酸盐的作用需要进一步研究。
相似文献
1
2
Cell patterns in the surface of rabbit articular cartilage revealed by the backscatter mode of scanning electron microscopy.扫描电子显微镜背散射模式揭示的兔关节软骨表面细胞模式。
J Orthop Res. 1991 Mar;9(2):275-83. doi: 10.1002/jor.1100090216.
3
Experimental production of ridges on rabbit articular cartilage: a scanning electron microscope study.兔关节软骨上隆起的实验性产生：一项扫描电子显微镜研究
J Anat. 1976 Feb;121(Pt 1):119-32.
4
Humps on young human and rabbit articular cartilage.年轻人类和兔关节软骨上的隆突。
J Anat. 1977 Nov;124(Pt 2):425-35.
5
6
Comparison of the effects of steroid, aspirin and sodium salicylate on articular cartilage.类固醇、阿司匹林和水杨酸钠对关节软骨影响的比较。
Clin Orthop Relat Res. 1975 Jan-Feb(106):350-6. doi: 10.1097/00003086-197501000-00047.
7
The surface of dog articular cartilage: a scanning electron microscope study.犬关节软骨表面：扫描电子显微镜研究
J Anat. 1977 Apr;123(Pt 2):527-36.
8
Long-term results of superficial defects in articular cartilage: a scanning electron-microscope study.
J Pathol. 1977 Apr;121(4):213-7. doi: 10.1002/path.1711210404.
9
Cryoscanning electron microscopic study of the surface amorphous layer of articular cartilage.关节软骨表面无定形层的低温扫描电子显微镜研究
J Anat. 1995 Oct;187 ( Pt 2)(Pt 2):429-44.
10
The effects of ketorolac and morphine on articular cartilage and synovium in the rabbit knee joint.酮咯酸和吗啡对兔膝关节软骨和滑膜的影响。
Can J Physiol Pharmacol. 2004 Jul;82(7):502-5. doi: 10.1139/y04-066.
引用本文的文献
1
The Combined Use of Triamcinolone and Platelet-Rich Plasma in Equine Metacarpophalangeal Joint Osteoarthritis Treatments: An In Vivo and In Vitro Study.曲安奈德与富血小板血浆联合用于马掌指关节骨关节炎治疗的体内外研究
Animals (Basel). 2024 Dec 17;14(24):3645. doi: 10.3390/ani14243645.
2
Chondrotoxicity of Intra-Articular Injection Treatment: A Scoping Review.关节内注射治疗的软骨毒性：范围综述。
Int J Mol Sci. 2024 Jun 26;25(13):7010. doi: 10.3390/ijms25137010.
3
Local Effects Following Single and Repeat Intra-Articular Injections of Triamcinolone Acetonide Extended-Release: Results from Three Nonclinical Toxicity Studies in Dogs.曲安奈德缓释剂单次及重复关节腔内注射后的局部效应：来自三项犬类非临床毒性研究的结果
Rheumatol Ther. 2018 Dec;5(2):475-498. doi: 10.1007/s40744-018-0125-3. Epub 2018 Sep 10.
4
The Effect of Intra-articular Corticosteroids on Articular Cartilage: A Systematic Review.关节内皮质类固醇对关节软骨的影响：系统评价。
Orthop J Sports Med. 2015 Apr 27;3(5):2325967115581163. doi: 10.1177/2325967115581163. eCollection 2015 May.
5
The chondrotoxicity of single-dose corticosteroids.单次剂量皮质类固醇的软骨毒性。
Knee Surg Sports Traumatol Arthrosc. 2012 Sep;20(9):1809-14. doi: 10.1007/s00167-011-1820-6. Epub 2011 Dec 21.
6
The effect of local anesthetic and corticosteroid combinations on chondrocyte viability.局部麻醉药和皮质类固醇联合应用对软骨细胞活力的影响。
Knee Surg Sports Traumatol Arthrosc. 2012 Sep;20(9):1689-95. doi: 10.1007/s00167-011-1728-1. Epub 2011 Oct 29.
7
The effect of local corticosteroid or ketorolac exposure on histologic and biomechanical properties of rabbit tendon and cartilage.局部使用皮质类固醇或酮咯酸对兔肌腱和软骨的组织学及生物力学特性的影响。
Hand (N Y). 2007 Dec;2(4):165-72. doi: 10.1007/s11552-007-9042-6. Epub 2007 May 5.
8
Physiological levels of hydrocortisone maintain an optimal chondrocyte extracellular matrix metabolism.生理水平的氢化可的松维持软骨细胞外基质的最佳代谢。
Ann Rheum Dis. 2004 Jan;63(1):61-6. doi: 10.1136/ard.2002.005298.
本文引用的文献
1
Charcot-like arthropathy following intra-articular hydrocortisone.关节内注射氢化可的松后出现的夏科氏关节病样关节病。
JAMA. 1962 Sep 8;181:851-4. doi: 10.1001/jama.1962.03050360037007.
2
Electron microscopy of articular cartilage in the young adult rabbit.成年幼兔关节软骨的电子显微镜检查
Ann Rheum Dis. 1962 Mar;21(1):11-22. doi: 10.1136/ard.21.1.11.
3
Steroid arthropathy of the hip.髋关节类固醇性关节病
Br Med J. 1960 May 7;1(5183):1392-4. doi: 10.1136/bmj.1.5183.1392.
4
Charcot's arthropathy following intra-articular hydrocortisone.关节内注射氢化可的松后发生的夏科氏关节病。
Br Med J. 1959 Apr 11;1(5127):952-3. doi: 10.1136/bmj.1.5127.952.
5
Hydrocortisone arthropathy--an experimental investigation.氢化可的松性关节病——一项实验研究
Can Med Assoc J. 1967 Aug 19;97(8):374-7.
6
The fine structure of chondrocytes.软骨细胞的精细结构。
J Anat. 1966 Apr;100(Pt 2):213-26.
7
Steroid arthropathy.类固醇性关节病
Radiology. 1966 Apr;86(4):652-7. doi: 10.1148/86.4.652.
8
Fine structure of articular cartilage in mice receiving cortisone acetate.
Arch Pathol. 1966 Dec;82(6):569-82.
9
The acute effects of intra-articular hydrocortisone on articular cartilage in rabbits.关节内注射氢化可的松对兔关节软骨的急性影响。
J Bone Joint Surg Am. 1966 Oct;48(7):1383-8.
10
Salicylate inhibition of cartilage degeneration.水杨酸盐对软骨退变的抑制作用。
Arthritis Rheum. 1965 Oct;8(5):960-9. doi: 10.1002/art.1780080506.
Zotero 插件