星形胶质细胞膜结构：循环停止后的变化。
Astrocyte membrane structure: changes after circulatory arrest.
作者信息
Landis D M, Reese T S
出版信息
J Cell Biol. 1981 Mar;88(3):660-3. doi: 10.1083/jcb.88.3.660.
Abstract
Membranes of the astrocytic processes investing small blood vessels and the surface of the brain contain numerous arrays of orthogonally packed particles as revealed by the freeze-fracture technique. The structure of these particle arrays, which we have termed "assemblies," is the same whether tissue is prepared for freeze-fracture by conventional fixation or by quick excision and rapid freezing. However, assemblies are progressively replaced by amorphous clumps and then disappear as the interval between decapitation and rapid freezing increases. Nearly normal numbers of assemblies may be maintained in cerebellar slices in vitro, but there too they disappear at low PO2 or in the presence of dinitrophenol. No other neuronal or glial membrane specialization exhibits a comparable lability.
摘要
通过冷冻断裂技术揭示，包绕小血管和脑表面的星形胶质细胞突起的膜含有大量正交排列的颗粒阵列。这些颗粒阵列的结构，我们称之为“组装体”，无论组织是通过传统固定还是快速切除和快速冷冻来制备用于冷冻断裂，其结构都是相同的。然而，随着断头和快速冷冻之间的时间间隔增加，组装体逐渐被无定形团块取代，然后消失。在体外小脑切片中，组装体的数量可维持在接近正常水平，但在低氧分压或存在二硝基苯酚的情况下，它们也会消失。没有其他神经元或神经胶质细胞膜特化表现出类似的不稳定性。
相似文献
1
Astrocyte membrane structure: changes after circulatory arrest.星形胶质细胞膜结构：循环停止后的变化。
J Cell Biol. 1981 Mar;88(3):660-3. doi: 10.1083/jcb.88.3.660.
2
Regional organization of astrocytic membranes in cerebellar cortex.小脑皮质中星形胶质细胞膜的区域组织
Neuroscience. 1982 Apr;7(4):937-50. doi: 10.1016/0306-4522(82)90053-7.
3
Freeze-fracture studies of plasma membranes of astrocytes in freezing lesions.冷冻损伤中星形胶质细胞质膜的冷冻断裂研究。
Adv Neurol. 1986;44:765-74.
4
Substructure in the assemblies of intramembrane particles in astrocytic membranes.
J Neurocytol. 1989 Dec;18(6):819-31. doi: 10.1007/BF01187234.
5
Freeze-fracture analysis of plasma membranes of isolated astrocytes from rat brain.大鼠脑分离星形胶质细胞质膜的冰冻断裂分析
Brain Res. 1983 Nov 14;278(1-2):81-91. doi: 10.1016/0006-8993(83)90226-3.
6
Effects of dexamethasone on the differentiation of membrane structure in cultured astrocytes.地塞米松对培养星形胶质细胞中膜结构分化的影响。
Glia. 1991;4(4):335-44. doi: 10.1002/glia.440040402.
7
Membrane structure in mammalian astrocytes: a review of freeze-fracture studies on adult, developing, reactive and cultured astrocytes.
J Exp Biol. 1981 Dec;95:35-48. doi: 10.1242/jeb.95.1.35.
8
Disturbance of plasmalemmal astrocytic assemblies in focal and selective cerebral ischemia.局灶性和选择性脑缺血时质膜星形胶质细胞集合体的紊乱
Anat Embryol (Berl). 1985;172(2):171-5. doi: 10.1007/BF00319599.
9
Particle assemblies in astrocytic plasma membranes are rearranged by various agents in vitro and cold injury in vivo.星形胶质细胞质膜中的颗粒聚集体在体外可被多种试剂重排，在体内可被冷损伤重排。
J Neurocytol. 1982 Dec;11(6):1009-29. doi: 10.1007/BF01148314.
10
Specialization of astrocytic membrane at glia limitans in rat optic nerve: freeze-fracture observations.
Neurosci Lett. 1985 Apr 19;55(3):371-8. doi: 10.1016/0304-3940(85)90464-1.
引用本文的文献
1
Cryopreservation of brain cell structure: a review.脑细胞结构的冷冻保存：综述
Free Neuropathol. 2024 Dec 11;5:35. doi: 10.17879/freeneuropathology-2024-5883. eCollection 2024 Jan.
2
Spatial model of convective solute transport in brain extracellular space does not support a "glymphatic" mechanism.脑细胞外空间对流溶质转运的空间模型不支持“类淋巴”机制。
J Gen Physiol. 2016 Dec;148(6):489-501. doi: 10.1085/jgp.201611684. Epub 2016 Nov 11.
3
Aggregation state determines the localization and function of M1- and M23-aquaporin-4 in astrocytes.聚集状态决定了星形胶质细胞中M1和M23水通道蛋白4的定位和功能。
J Cell Biol. 2014 Feb 17;204(4):559-73. doi: 10.1083/jcb.201308118. Epub 2014 Feb 10.
4
Aquaporin expression in normal and pathological skeletal muscles: a brief review with focus on AQP4.水通道蛋白在正常和病理骨骼肌中的表达：以水通道蛋白4为重点的简要综述
J Biomed Biotechnol. 2010;2010:731569. doi: 10.1155/2010/731569. Epub 2010 Mar 21.
5
Differential water permeability and regulation of three aquaporin 4 isoforms.三种水通道蛋白 4 异构体的差异水通透性和调节。
Cell Mol Life Sci. 2010 Mar;67(5):829-40. doi: 10.1007/s00018-009-0218-9. Epub 2009 Dec 15.
6
Acute vascular disruption and aquaporin 4 loss after stroke.中风后的急性血管破坏和水通道蛋白4缺失
Stroke. 2009 Jun;40(6):2182-90. doi: 10.1161/STROKEAHA.108.523720. Epub 2009 Apr 16.
7
Aquaporin-4 square array assembly: opposing actions of M1 and M23 isoforms.水通道蛋白4方形阵列组装：M1和M23亚型的相反作用。
Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13609-14. doi: 10.1073/pnas.2235843100. Epub 2003 Nov 3.
8
Polarized trafficking and surface expression of the AQP4 water channel are coordinated by serial and regulated interactions with different clathrin-adaptor complexes.水通道蛋白4（AQP4）的极化运输和表面表达通过与不同网格蛋白衔接复合物的一系列受调控的相互作用来协调。
EMBO J. 2001 Dec 17;20(24):7008-21. doi: 10.1093/emboj/20.24.7008.
9
Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord.大鼠脑和脊髓中星形胶质细胞和室管膜细胞质膜方阵中水通道蛋白-4的直接免疫金标记。
Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11981-6. doi: 10.1073/pnas.95.20.11981.
10
On the structural organization of isolated bovine lens fiber junctions.关于分离的牛晶状体纤维连接的结构组织
J Cell Biol. 1982 Apr;93(1):175-89. doi: 10.1083/jcb.93.1.175.
本文引用的文献
1
A STUDY OF EXTRACELLULAR SPACE IN CENTRAL NERVOUS TISSUE BY FREEZE-SUBSTITUTION.用冷冻置换法对中枢神经组织细胞外间隙的研究
J Cell Biol. 1965 Apr;25(1):117-37. doi: 10.1083/jcb.25.1.117.
2
ELECTRON MICROSCOPY AFTER RAPID FREEZING ON A METAL SURFACE AND SUBSTITUTION FIXATION.在金属表面快速冷冻及置换固定后的电子显微镜检查
Anat Rec. 1964 Jul;149:381-5. doi: 10.1002/ar.1091490307.
3
Junctions between intimately apposed cell membranes in the vertebrate brain.脊椎动物大脑中紧密相邻细胞膜之间的连接。
J Cell Biol. 1969 Mar;40(3):648-77. doi: 10.1083/jcb.40.3.648.
4
Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection.动脉注射后放射性标记氨基酸、胺类和己糖的脑摄取情况。
Am J Physiol. 1971 Dec;221(6):1629-39. doi: 10.1152/ajplegacy.1971.221.6.1629.
5
Arrays of particles in freeze-fractured astrocytic membranes.冷冻断裂星形胶质细胞膜中的颗粒阵列。
J Cell Biol. 1974 Jan;60(1):316-20. doi: 10.1083/jcb.60.1.316.
6
Functional changes in frog neuromuscular junctions studied with freeze-fracture.用冷冻断裂法研究青蛙神经肌肉接头的功能变化。
J Neurocytol. 1974 Mar;3(1):109-31. doi: 10.1007/BF01111936.
7
Three types of gap junctions interconnecting intestinal epithelial cells visualized by freeze-etching.通过冷冻蚀刻观察到的连接肠上皮细胞的三种间隙连接类型。
Proc Natl Acad Sci U S A. 1972 May;69(5):1318-21. doi: 10.1073/pnas.69.5.1318.
8
Studies of excitable membranes. I. Macromolecular specializations of the neuromuscular junction and the nonjunctional sarcolemma.可兴奋膜的研究。I. 神经肌肉接头和非接头肌膜的大分子特化
J Cell Biol. 1974 Nov;63(2 Pt 1):567-86. doi: 10.1083/jcb.63.2.567.
9
Specific plasma membrane differentiations in the cells of the kidney collecting tubule.肾集合管细胞中的特定质膜分化。
J Ultrastruct Res. 1975 Jul;52(1):13-20. doi: 10.1016/s0022-5320(75)80018-9.
10
Preservation of synaptic structure by rapid freezing.
Cold Spring Harb Symp Quant Biol. 1976;40:17-24. doi: 10.1101/sqb.1976.040.01.004.
Zotero 插件