Brindley G S, Craggs M D
J Neurol Neurosurg Psychiatry. 1980 Dec;43(12):1083-90. doi: 10.1136/jnnp.43.12.1083.
If a spinal root of a baboon or rhesus monkey is trapped in an initially loose-fitting silicone rubber channel containing two or more platinum electrodes, electrical pulses sent through these electrodes can stimulate nerve fibres close to the cathode and block the resulting impulses close to the anode. We show (1) how anodal break excitation and excitation of fibres outside the silicone rubber channel can be avoided; (2) that an implant 26 months old behaves like a recent one; (3) that in a root containing somatic motor fibres and parasympathetic fibres, all somatic motor fibres can be blocked and most or all parasympathetic fibres excited but not blocked; (4) that provided that the electrodes pass no net direct current, prolonged stimulation with block can be harmless; (5) how block can be achieved in one direction only along a root; (6) that a peripheral nerve can be blocked by the same techniques.
如果将狒狒或恒河猴的脊神经根置于一个最初宽松适配的、包含两个或更多铂电极的硅橡胶通道中，通过这些电极发送的电脉冲可刺激靠近阴极的神经纤维，并在靠近阳极处阻断产生的冲动。我们展示了：（1）如何避免阳极断电兴奋和硅橡胶通道外纤维的兴奋；（2）植入26个月的装置表现与近期植入的装置相同；（3）在包含躯体运动纤维和副交感纤维的神经根中，所有躯体运动纤维均可被阻断，且大多数或所有副交感纤维可被兴奋但不会被阻断；（4）只要电极不通过净直流电，长时间的阻断刺激可能是无害的；（5）如何仅沿神经根在一个方向上实现阻断；（6）相同的技术可用于阻断外周神经。
