Birch D F, Fairley K F, Pavillard R E
Kidney Int. 1981 Jan;19(1):58-64. doi: 10.1038/ki.1981.7.
Bladder-aspirate urine samples (N = 428) were cultured for the presence of fastidious microorganisms. These samples were obtained from 190 patients with urinary tract disease or symptoms suggesting infection of the urinary tract in whom standard bacteriologic investigation had failed to indicate bacterial infection. Ureaplasma urealyticum was recovered alone or in association with other microorganisms from the bladder urine of 75% of patients with reflux scarring and abnormal renal function. Ureaplasma organisms were localized to the upper urinary tract in 80% of patients with bladder counts greater than 10(3) colony-forming units per ml. The results indicate that microorganisms not conventionally associated with urinary tract infection are recoverable from the bladder urine of a high percentage of patients with so-called "sterile pyelonephritis," in which group of patients these microorganisms may contribute to progressive renal disease.
对膀胱穿刺尿液样本（N = 428）进行培养，以检测苛养微生物的存在。这些样本取自190例患有泌尿系统疾病或有提示泌尿系统感染症状的患者，其标准细菌学检查未能显示细菌感染。在75%有反流性瘢痕和肾功能异常的患者的膀胱尿液中，单独或与其他微生物一起检出解脲脲原体。在膀胱菌落计数大于每毫升10³ 菌落形成单位的患者中，80%的解脲脲原体定位于上尿路。结果表明，在高比例的所谓“无菌性肾盂肾炎”患者的膀胱尿液中可检出通常与尿路感染无关的微生物，在这些患者中，这些微生物可能导致进行性肾病。
