Wahner H W, Kyle R A, Beabout J W
Mayo Clin Proc. 1980 Dec;55(12):739-46.
The effectiveness of bone scintigraphy for the detection of skeletal involvement in multiple myeloma was studied in 27 patients. Bone scintigrams and roentgenographic surveys were performed every 6 months for a period of 5 years or less, depending on the final course of the disease. This group was compared with a group of 100 patients with prostatic cancer at the time of initial diagnosis. In the myeloma group, roentgenographic skeletal surveys indicated bone involvement with greater specificity and sensitivity at the time of the initial diagnosis, in follow-up studies, and in the evaluation of bone pain than did scintigrams. In contrast to results in prostatic cancer, the bone scan added little to the management of patients with multiple myeloma.
对27例多发性骨髓瘤患者进行了骨闪烁显像检测骨骼受累情况的有效性研究。根据疾病的最终病程，每6个月进行一次骨闪烁显像和X线检查，为期5年或更短时间。将该组患者与100例前列腺癌初诊患者进行比较。在骨髓瘤组中，X线骨骼检查在初始诊断、随访研究以及骨痛评估时，显示出比闪烁显像更高的骨骼受累特异性和敏感性。与前列腺癌的结果相反，骨扫描对多发性骨髓瘤患者的治疗帮助不大。
