Woolfenden J M, Pitt M J, Durie B G, Moon T E
Radiology. 1980 Mar;134(3):723-8. doi: 10.1148/radiology.134.3.7355226.
Radionuclide images and skeletal radiographs of 51 patients with multiple myeloma were compared to assess the sensitivity of scintigraphy in detecting radiographically evident disease. Comparable studies were available for 562 sites. The radionuclide image was relatively insensitive in detecting myeloma; it failed to show radiographically evident disease or underestimated its extent at 27% of the sites. On a limited number of serial images there were 7 sites at which a scintigraphic abnormality preceded the radiographic abnormality. No definite correlation was found between scintigraphic findings and hematologic parameters of myeloma activity. Although the radionuclide image may demonstrate a few sites of myeloma before the radiograph, radiography remains the primary method of evaluating skeletal involvement by myeloma.
对51例多发性骨髓瘤患者的放射性核素图像和骨骼X光片进行比较，以评估闪烁扫描术在检测X线可见病变方面的敏感性。有562个部位的可比研究资料。放射性核素图像在检测骨髓瘤方面相对不敏感；在27%的部位未能显示出X线可见病变或低估了其范围。在数量有限的系列图像中，有7个部位闪烁扫描异常先于X线异常出现。未发现闪烁扫描结果与骨髓瘤活动的血液学参数之间有明确的相关性。尽管放射性核素图像可能在X光片之前显示出少数骨髓瘤部位，但X光检查仍然是评估骨髓瘤骨骼受累情况的主要方法。
