Frank K, Bettendorf U, Reinhardt P
Leber Magen Darm. 1981 Jan;11(1):37-43.
A case report is given of a malignant melanoma of the esophagus and the symptoms of this tumor are reviewed on the basis of 62 cases from the world literature. Males were afflicted 1.7 times as often as females. 85% of all patients were between the ages of 50 and 75. Symptoms, localization, and pattern of metastases are essentially similar to esophageal carcinoma. Melanoma grows like polyps in most cases and does have the typical histological pattern with differing amounts of pigmentation; pigmentation may be difficult to diagnose endoscopically. The esophageal melanoma apparently originate from intraepithelial foci of melanoma cells, which can be found in the neighbourhood of melanomas in macroscopically intact mucosa.
本文报告了一例食管恶性黑色素瘤病例，并根据世界文献中的62例病例回顾了该肿瘤的症状。男性患病几率是女性的1.7倍。所有患者中85%年龄在50至75岁之间。症状、定位及转移模式与食管癌基本相似。黑色素瘤在大多数情况下呈息肉样生长，具有典型的组织学模式，色素沉着量各不相同；色素沉着在内镜检查时可能难以诊断。食管黑色素瘤显然起源于黑色素瘤细胞的上皮内病灶，在宏观上完整的黏膜中黑色素瘤附近可发现这些病灶。
