Combe N, Constantin M J, Entressangles B
Lipids. 1981 Jan;16(1):8-14. doi: 10.1007/BF02534914.
The lymphatic absorption of nonvolatile oxidation products (NVOP) formed during heating of fats was studied. Heated colza or soybean oils or synthetic triglycerides containing a definite aromatic or alicyclic fatty acid were fed to thoracic duct-cannulated rats. Tritium-labeled triolein was added to each dietary fat, as an internal standard, in order to calculate the percentage of lymphatic absorption of the ingested NVOP. Results show that 4% of the total polymeric acids, 53% of the total oxidized monomeric acids and 96% of the total cyclic monomeric acids were recovered in the lymphatic lipids. Gas liquid and quantitative thin layer chromatography of these 3 classes indicated that, within a NVOP class, the various constituents did not present the same absorption rate. The lymphatic absorptions of individual oxidized monomers were between 25 and 93%. Concerning the polymer fraction, the lymphatic recoveries were 1% (nonpolar dimers), 6.8% (polar dimers) and 12% (polar oligomers). Aromatic acids were absorbed to a lesser degree (50-60%) than cyclohexenic acids (91-98%).
研究了脂肪加热过程中形成的非挥发性氧化产物（NVOP）的淋巴吸收情况。将加热的菜籽油或大豆油或含有特定芳香族或脂环族脂肪酸的合成甘油三酯喂给胸导管插管大鼠。将氚标记的三油酸甘油酯作为内标添加到每种膳食脂肪中，以计算摄入的NVOP的淋巴吸收百分比。结果表明，在淋巴脂质中回收了4% 的总聚合酸、53% 的总氧化单体酸和96% 的总环状单体酸。这三类物质的气液色谱和定量薄层色谱表明，在NVOP类别中，各种成分的吸收率不同。单个氧化单体的淋巴吸收率在25% 至93% 之间。关于聚合物部分，淋巴回收率分别为1%（非极性二聚体）、6.8%（极性二聚体）和12%（极性低聚物）。芳香酸的吸收程度（50-60%）低于环己烯酸（91-98%）。
