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多发性硬化症:家猫与之有关吗?

Multiple sclerosis: is the domestic cat involved?

作者信息

Cook R D

出版信息

Med Hypotheses. 1981 Feb;7(2):147-54. doi: 10.1016/0306-9877(81)90111-0.

Abstract

Recent evidence suggests a possible viral aetiology of multiple sclerosis (MS). The present hypothesis proposes a relationship between MS and a demyelinating condition in the central nervous system of cats from which a paramyxovirus has been isolated. The theory attempts to relate the distribution and incidence of MS with the keeping of cats as household pets. The incidence of MS is explained on the basis of a human susceptibility factor, perhaps the histocompatibility antigens and the onset, remissions and relapse of MS are considered to be related to stressful situations which trigger a persistent virus.

摘要

最近的证据表明多发性硬化症(MS)可能存在病毒病因。目前的假说提出了MS与猫中枢神经系统脱髓鞘疾病之间的关系,从这种疾病中已分离出一种副粘病毒。该理论试图将MS的分布和发病率与养猫作为家庭宠物联系起来。MS的发病率是基于人类易感性因素来解释的,可能是组织相容性抗原,并且MS的发作、缓解和复发被认为与引发持续性病毒的应激情况有关。

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