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[脑干蓝斑刺激后节段反射的变化及儿茶酚胺作用的增强]

[Changes in segmental reflexes upon stimulation of the locus coeruleus of the brain stem and potentiation of catecholamine action].

作者信息

Iakhnitsa I A

出版信息

Neirofiziologiia. 1981;13(1):39-47.

PMID:7219604
Abstract

Rhythmic stimulation of locus coeruleus was accompanied by a depressed inhibitory action of flexor reflex afferents and recurrent inhibition on extensor motoneurons in anaesthetized and decerebellized cats. Such stimulation had no essential effect on the direct inhibition of extensor and flexor motoneurons, on the excitatory action of flexor reflex afferents and recurrent inhibition on the flexor motoneurons. The injection of pyrogallol caused similar effect but it was greatly diminished by cold blockage or transsection of the spinal cord. The experiments with partial cuts of the spinal cord to consider the effects as a result of activation of coerulo-spinal pathway which descend in the ventral quadrant of the spinal cord.

摘要

在麻醉和去小脑的猫中,对蓝斑进行节律性刺激时,屈肌反射传入纤维的抑制作用以及伸肌运动神经元的回返抑制均受到抑制。这种刺激对伸肌和屈肌运动神经元的直接抑制、屈肌反射传入纤维的兴奋作用以及屈肌运动神经元的回返抑制均无实质性影响。注射连苯三酚也产生了类似的效果,但通过脊髓冷阻断或横断,这种效果会大大减弱。通过部分切断脊髓进行实验,以研究脊髓腹侧象限下行的蓝斑 - 脊髓通路激活所产生的影响。

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