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[蓝斑节律性刺激对猫屈肌反射传入纤维激活所致脊髓抑制的影响]

[Effect of rhythmic stimulation of the locus coeruleus on spinal inhibition induced by activation of flexor reflex afferents in the cat].

作者信息

Piliavskiĭ A I, Gokin A P, Iakhnitsa I A

出版信息

Neirofiziologiia. 1981;13(2):187-95.

PMID:7231607
Abstract

Locus coeruleus rhythmic stimulation of 40/s frequency and 50-150 micro A current intensity diminished the inhibitory action from flexor reflex afferents on extensor monosynaptic reflexes in anaesthetized decerebellized cats. Such an effect appeared 600 ms after and reached maximum 1500-1700 ms after the locus coeruleus stimulation. The depression of inhibition was maintained during 2-3 s after cessation of the stimulation. No effect was observed when locus coeruleus was stimulated by a single stimulus or by a short high-frequency pulse train of the same current strength. An increase of the stimulation intensity evoked activation of neighbouring structures. The advantages of the rhythmic stimulation for revealing the influences of slow conducting pathways are discussed.

摘要

在麻醉去小脑猫中,蓝斑以40次/秒的频率和50 - 150微安的电流强度进行节律性刺激,减弱了屈肌反射传入纤维对伸肌单突触反射的抑制作用。这种效应在蓝斑刺激后600毫秒出现,并在刺激后1500 - 1700毫秒达到最大值。刺激停止后,抑制作用的减弱持续2 - 3秒。当用单个刺激或相同电流强度的短高频脉冲串刺激蓝斑时,未观察到效应。刺激强度增加会引起相邻结构的激活。讨论了节律性刺激在揭示慢传导通路影响方面的优势。

相似文献

1
[Effect of rhythmic stimulation of the locus coeruleus on spinal inhibition induced by activation of flexor reflex afferents in the cat].[蓝斑节律性刺激对猫屈肌反射传入纤维激活所致脊髓抑制的影响]
Neirofiziologiia. 1981;13(2):187-95.
2
[Changes in inhibitory responses in the spinal cord of the cat induced by stimulation of suprasegmental structures during rhythmic stimulation of the locus coeruleus].[在蓝斑节律性刺激期间刺激节段上结构诱发的猫脊髓抑制性反应的变化]
Neirofiziologiia. 1983;15(1):65-70.
3
[Effect of rhythmic stimulation of the locus coeruleus on segmental reflex reactions evoked by stimulation of cutaneous and muscle afferents].[蓝斑节律性刺激对皮肤和肌肉传入神经刺激诱发的节段性反射反应的影响]
Neirofiziologiia. 1980;12(6):642-5.
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[Changes in segmental reflexes upon stimulation of the locus coeruleus of the brain stem and potentiation of catecholamine action].[脑干蓝斑刺激后节段反射的变化及儿茶酚胺作用的增强]
Neirofiziologiia. 1981;13(1):39-47.
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[Effect of stimulation of the locus coeruleus and adjacent portions of the brain stem on inhibition of segmental reflexes].[蓝斑及脑干相邻部位刺激对节段性反射抑制的影响]
Neirofiziologiia. 1980;12(6):646-9.
6
[Changes in the postsynaptic responses of spinal cord motor neurons against a background of rhythmic stimulation of the locus coeruleus].[在蓝斑节律性刺激背景下脊髓运动神经元突触后反应的变化]
Neirofiziologiia. 1982;14(1):51-9.
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[Effect of drugs potentiating or inhibiting the activity of locus coeruleus neurons on various types of spinal inhibition in the cat].[增强或抑制蓝斑神经元活性的药物对猫各种类型脊髓抑制的作用]
Neirofiziologiia. 1981;13(3):247-58.
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Reflex mechanisms of interlimb interrelationships displayed in lumbar flexor centers of the cat spinal cord.猫脊髓腰段屈肌中枢中显示的肢体间相互关系的反射机制。
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