Di Nola F, Capra E, Soranzo M L, Bosio G, Bramato C, Salassa B, Andrini L, Andreoni G, Eandi M, Musso E
Minerva Med. 1981 Apr 14;72(15):941-50.
A mean plasma concentration curve, with peaks within the first hour and moderate individual variations, was obtained after a single administration of 800 mg of bacampicillin to 5 healthy volunteers. An adequate antibiotic transfer from the circulation to the bronchial apparatus was demonstrated. Treatment of 34 patients suffering from ampicillin-sensitive bacterial diseases permitted clinical cure of all patients, without onset of side-effects. It is concluded that bacampicillin is preferable to oral ampicillin because of its kinetic and tolerance features.
