Vaziri N D, Barton C H, Ness R, Clark D
J Dial. 1978;2(3):243-9. doi: 10.3109/08860227809080090.
We have shown that theophylline is highly dialysable with an average dialysis clearance of 76 ml/min approaching 63% of urea clearance with hemodialysis. Implications include dose adjustment during dialysis and efficacy of dialytic technique in the treatment of theophylline intoxication.
我们已经表明,茶碱具有高度的可透析性,血液透析时平均透析清除率为76毫升/分钟,接近尿素清除率的63%。这意味着在透析期间需要调整剂量,以及透析技术在治疗茶碱中毒方面的有效性。