Ferlito A, Carbone A, Volpe R
ORL J Otorhinolaryngol Relat Spec. 1981;43(2):61-78. doi: 10.1159/000275528.
The present paper reports the clinicopathologic features of six cases of non-Hodgkin's lymphoma of the larynx observed during the last 14 years. After careful clinical staging only 3 patients had isolated laryngeal lymphoma (stage IE). Radiotherapy was administered as initial treatment in all cases. These patients are alive and well after 12, 6 and 1 years, respectively. Histologically, all laryngeal lymphomas of this study showed a diffuse pattern of growth. All lymphomas were of follicular center cell origin according to Lukes and Collins (29). Four cases were of low grade malignancy according to Lennert and Mohri (25), or grade I, according to the British (18) classification. The remaining two were of high grade malignancy or grade II. A careful histopathological diagnosis, which may separate other pathological conditions, and an appropriate staging, which may exclude dissemination of disease, are stressed as representing the basis for effective treatment. The applicability of current functional nomenclature is possible also in these extranodal lymphomas.
本文报告了过去14年间观察到的6例喉非霍奇金淋巴瘤的临床病理特征。经过仔细的临床分期，仅有3例患者为孤立性喉淋巴瘤（IE期）。所有病例均以放射治疗作为初始治疗。这些患者分别在12年、6年和1年后仍存活且状况良好。组织学上，本研究中的所有喉淋巴瘤均呈弥漫性生长模式。根据Lukes和Collins（29）的分类，所有淋巴瘤均起源于滤泡中心细胞。根据Lennert和Mohri（25）的分类，4例为低级别恶性，或根据英国（18）分类为I级。其余2例为高级别恶性或II级。强调仔细的组织病理学诊断（可区分其他病理状况）和适当的分期（可排除疾病播散）是有效治疗的基础。当前的功能命名法在这些结外淋巴瘤中也适用。
