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儿童白血病和淋巴瘤脑脊液细胞学评估(作者译)

[An evaluation of cerebrospinal fluid cytology in childhood leukaemias and lymphomas (author's transl)].

作者信息

Mouriquand C, Bachelot C, Breyton M, Girardot P

出版信息

Nouv Presse Med. 1981 Feb 14;10(6):391-4.

PMID:7220331
Abstract

A cytological study of the cerebrospinal fluid was carried out on 72 children with leukaemia or lymphoma either at the onset or during the course of the disease. It proved extremely useful in revealing the presence of malignant cells in CSF's with normal cell count and in distinguishing with absolute certainty meningeal leukaemias from meningeal reactions of other origins, in particular the frequent histiocytic reactions to radiotherapy and/or chemotherapy. These "irritative" reactions are a reminder that iatrogenic damage to the central nervous system is a distinct possibility, and the modalities of treatment should perhaps be reconsidered when they attain a certain magnitude.

摘要

对72例白血病或淋巴瘤患儿在疾病发作时或病程中进行了脑脊液细胞学研究。结果证明,该研究对于发现细胞计数正常的脑脊液中存在恶性细胞,以及明确区分脑膜白血病与其他原因引起的脑膜反应(尤其是放疗和/或化疗后常见的组织细胞反应)极为有用。这些“刺激性”反应提醒人们,中枢神经系统发生医源性损伤是完全有可能的,当这类反应达到一定程度时,或许应该重新考虑治疗方式。

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