Lucas M, Osuna C, Goberna R
Rev Esp Fisiol. 1980 Dec;36(4):403-7.
Rat liver mitochondria from fed and 4-day-fasted rats are able to accumulate calcium supported by ATP (energy-driven calcium uptake) or by succinate (respiration-driven calcium uptake). Phosphoenolpyruvate decreases the amount of calcium accumulated in both ways, whether the rats were fasted or fed ad libitum. Phosphoenolpyruvate induces a net calcium efflux from mitochondria. The effect of phosphoenolpyruvate is partially reversed by ADP. Phosphoenolpyruvate is also able to inhibit the ATP-driven calcium accumulation in the absence of exogenously added respiratory substrates.
来自喂食和禁食4天的大鼠的肝线粒体能够在ATP（能量驱动的钙摄取）或琥珀酸（呼吸驱动的钙摄取）的支持下积累钙。无论大鼠是禁食还是随意进食，磷酸烯醇丙酮酸都会以两种方式减少钙的积累量。磷酸烯醇丙酮酸诱导线粒体产生净钙外流。ADP可部分逆转磷酸烯醇丙酮酸的作用。在没有外源添加呼吸底物的情况下，磷酸烯醇丙酮酸也能够抑制ATP驱动的钙积累。
