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血细胞比容对慢性呼吸衰竭合并继发性红细胞增多症患者血液粘度的影响。

Effect of hematocrit on the blood viscosity of patients with chronic respiratory failure and secondary polycythemia.

作者信息

Clivati A, Marazzini L, Agosti R, Gatto R, Longhini E

出版信息

Respiration. 1980;40(4):201-7. doi: 10.1159/000194285.

DOI:10.1159/000194285
PMID:7221192
Abstract

The blood of patients with chronic global respiratory failure and polycythemia exhibits higher viscosity than that of normal subjects. Plasma changes have been excluded as causal factors. The viscosity of whole blood, plasma and blood after correction of hematocrit (Ht; 45%) with autologous plasma, has been determined. The results indicate that in such patients the increase in Ht is not the most important factor affecting the rheological properties (increased viscosity) of blood. A high Ht value may be only pat of the mechanism that increases the blood viscosity of patients with chronic obstructive pulmonary disease. There is evidence that other factors are responsible for increased blood viscosity in chronic respiratory failure.

摘要

慢性全肺呼吸衰竭合并红细胞增多症患者的血液比正常受试者的血液具有更高的粘度。血浆变化已被排除为致病因素。已测定全血、血浆以及用自体血浆校正血细胞比容(Ht;45%)后的血液粘度。结果表明,在此类患者中,Ht升高并非影响血液流变学特性(粘度增加)的最重要因素。高Ht值可能只是慢性阻塞性肺疾病患者血液粘度增加机制的一部分。有证据表明,其他因素导致慢性呼吸衰竭患者的血液粘度增加。

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Respiration. 1980;40(4):201-7. doi: 10.1159/000194285.
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