Marazzini L, Soroldoni M, Clivati A, Simonati O, Ogliari L, Brasca F, Agosti R, Longhini E
Respiration. 1981;42(3):168-74. doi: 10.1159/000194424.
Normovolemic hemodilution produced by isovolumetric venesection was done in 8 patients with polycythemia and respiratory failure secondary to chronic obstructive pulmonary disease. The 'deformability index' was studied by means of a filtration technique. The blood flow velocity in ascending aorta and right pulmonary artery was also studied by means of ultrasonic Echo-Doppler technique. The procedure showed in all patients an increase of oxygen tension and a decrease of carbonic gas tension in arterial blood. At the same time it was possible to demonstrate an improvement of red cell deformability and an increase of arterial flow velocity. Isovolumetric venesection is an important procedure in the management of patients with polycythemia secondary to respiratory failure.
对8例患有继发于慢性阻塞性肺疾病的红细胞增多症和呼吸衰竭的患者进行了等容放血造成的正常血容量血液稀释。通过过滤技术研究了“变形性指数”。还通过超声回声多普勒技术研究了升主动脉和右肺动脉中的血流速度。该操作在所有患者中均显示动脉血中氧分压升高和二氧化碳分压降低。同时，可以证明红细胞变形性得到改善且动脉血流速度增加。等容放血是治疗继发于呼吸衰竭的红细胞增多症患者的重要方法。
