由于直肠的其他衣原体感染，性病性淋巴肉芽肿直肠炎的血清学确诊可能会产生假阳性结果。

Confirmatory serodiagnosis of lymphogranuloma venereum proctitis may yield false-positive results due to other chlamydial infections of the rectum.

作者信息

Schachter J

出版信息

Sex Transm Dis. 1981 Jan-Mar;8(1):26-8. doi: 10.1097/00007435-198101000-00010.

DOI:10.1097/00007435-198101000-00010

Abstract

Chlamydia trachomatis was isolated from rectal swab specimens taken from six of 18 homosexual men with presumed lymphogranuloma venereum (LGV) proctitis. All 18 men met standard serologic criteria for the diagnosis of LGV (complement-fixing antibody titer, greater than 1:16; microimmunofluorescent IgG antibody titer, greater than 1:1,000). However, four of the six chlamydial isolates were non-LGV strains of C. trachomatis. It is suggested that these strains may cause proctitis and result in the exuberant antibody response associated with LGV. Thus, serologic confirmation of LGV proctitis may be "false-positive" in the sense that it reflects other chlamydial infections.

摘要

从18名疑似患有性病性淋巴肉芽肿（LGV）直肠炎的同性恋男性中的6人的直肠拭子标本中分离出沙眼衣原体。所有18名男性均符合LGV诊断的标准血清学标准（补体结合抗体滴度大于1:16；微量免疫荧光IgG抗体滴度大于1:1000）。然而，6株衣原体分离株中有4株是沙眼衣原体的非LGV菌株。有人提出，这些菌株可能引起直肠炎，并导致与LGV相关的旺盛抗体反应。因此，LGV直肠炎的血清学确诊在某种意义上可能是“假阳性”，因为它反映的是其他衣原体感染。