一个组氨酸残基的修饰对来自黑颈眼镜蛇蛇毒的有毒磷脂酶A2以及来自鼓腹咝蝰和中华眼镜蛇蛇毒的低毒磷脂酶A2的酶学和药理学特性的影响。 - Suppr

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超能文献

Effect of modification of one histidine residue on the enzymatic and pharmacological properties of a toxic phospholipase A2 from Naja nigricollis snake venom and less toxic phospholipases A2 from Hemachatus haemachatus and Naja atra snake venoms.

作者信息

Condrea E, Fletcher J E, Rapuano B E, Yang C C, Rosenberg P

出版信息

Toxicon. 1981;19(1):61-71. doi: 10.1016/0041-0101(81)90118-5.

DOI:10.1016/0041-0101(81)90118-5

PMID:7222090

Abstract

摘要

相似文献

Effect of modification of one histidine residue on the enzymatic and pharmacological properties of a toxic phospholipase A2 from Naja nigricollis snake venom and less toxic phospholipases A2 from Hemachatus haemachatus and Naja atra snake venoms.一个组氨酸残基的修饰对来自黑颈眼镜蛇蛇毒的有毒磷脂酶A2以及来自鼓腹咝蝰和中华眼镜蛇蛇毒的低毒磷脂酶A2的酶学和药理学特性的影响。

Toxicon. 1981;19(1):61-71. doi: 10.1016/0041-0101(81)90118-5.

Comparison of a relatively toxic phospholipase A2 from Naja nigricollis snake venom with that of a relatively non-toxic phospholipase A2 from Hemachatus haemachatus snake venom--II. Pharmacological properties in relationship to enzymatic activity.黑颈眼镜蛇蛇毒中一种相对有毒的磷脂酶A2与拟眼镜蛇蛇毒中一种相对无毒的磷脂酶A2的比较——II. 与酶活性相关的药理学特性

Biochem Pharmacol. 1980 Jun 1;29(11):1565-74. doi: 10.1016/0006-2952(80)90609-7.

Effect of carboxylate group modification on enzymatic and cardiotoxic properties of snake venom phospholipases A2.羧基修饰对蛇毒磷脂酶A2酶活性和心脏毒性的影响

Toxicon. 1984;22(5):743-58. doi: 10.1016/0041-0101(84)90157-0.

Comparison of a relatively toxic phospholipase A2 from Naja nigricollis snake venom with that of a relatively non-toxic phospholipase A2 from Hemachatus haemachatus snake venom--I. Enzymatic activity on free and membrane bound substrates.黑颈眼镜蛇蛇毒中一种相对有毒的磷脂酶A2与拟眼镜蛇蛇毒中一种相对无毒的磷脂酶A2的比较——I. 对游离和膜结合底物的酶活性

Biochem Pharmacol. 1980 Jun 1;29(11):1555-63. doi: 10.1016/0006-2952(80)90608-5.

Chemical modification of the histidine residue in phospholipase A2 from the Hemachatus haemachatus snake venom.

Toxicon. 1980;18(5-6):529-47. doi: 10.1016/0041-0101(80)90081-1.

The relationship between high-affinity noncatalytic binding of snake venom phospholipases A2 to brain synaptic plasma membranes and their central lethal potencies.蛇毒磷脂酶A2与脑突触质膜的高亲和力非催化结合与其中枢致死效力之间的关系。

Biochim Biophys Acta. 1986 Apr 25;856(3):457-70. doi: 10.1016/0005-2736(86)90137-9.

Effects of modification of tyrosines 3 and 62 (63) on enzymatic and toxicological properties of phospholipases A2 from Naja nigricollis and Naja naja atra snake venoms.酪氨酸3和62（63）的修饰对黑颈眼镜蛇和中华眼镜蛇蛇毒磷脂酶A2的酶学和毒理学特性的影响。

Toxicon. 1986;24(7):679-93. doi: 10.1016/0041-0101(86)90031-0.

Phospholipid hydrolysis in serum lipoproteins by a basic phospholipase A2 from Naja nigricollis snake venom and an acidic phospholipase A2 from Naja naja atra snake venom.眼镜蛇毒液中的碱性磷脂酶A2和眼镜王蛇毒液中的酸性磷脂酶A2对血清脂蛋白中磷脂的水解作用。

Toxicon. 1983;21(4):481-90. doi: 10.1016/0041-0101(83)90126-5.

Effect of methylation of histidine-48 on some enzymatic and pharmacological activities of snake venom phospholipases A2.

Life Sci. 1983 Mar 28;32(13):1455-61. doi: 10.1016/0024-3205(83)90911-6.

Dissociation of pharmacological and enzymatic activities of snake venom phospholipases A2 by modification of carboxylate groups.

Biochem Pharmacol. 1983 Dec 1;32(23):3525-30. doi: 10.1016/0006-2952(83)90298-8.

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