黑颈眼镜蛇蛇毒中一种相对有毒的磷脂酶A2与拟眼镜蛇蛇毒中一种相对无毒的磷脂酶A2的比较——II. 与酶活性相关的药理学特性 - Suppr

Suppr

超能文献

Comparison of a relatively toxic phospholipase A2 from Naja nigricollis snake venom with that of a relatively non-toxic phospholipase A2 from Hemachatus haemachatus snake venom--II. Pharmacological properties in relationship to enzymatic activity.

作者信息

Fletcher J E, Rapuano B E, Condrea E, Yang C C, Ryan M, Rosenberg P

出版信息

Biochem Pharmacol. 1980 Jun 1;29(11):1565-74. doi: 10.1016/0006-2952(80)90609-7.

DOI:10.1016/0006-2952(80)90609-7

PMID:7396987

Abstract

摘要

相似文献

Comparison of a relatively toxic phospholipase A2 from Naja nigricollis snake venom with that of a relatively non-toxic phospholipase A2 from Hemachatus haemachatus snake venom--II. Pharmacological properties in relationship to enzymatic activity.黑颈眼镜蛇蛇毒中一种相对有毒的磷脂酶A2与拟眼镜蛇蛇毒中一种相对无毒的磷脂酶A2的比较——II. 与酶活性相关的药理学特性

Biochem Pharmacol. 1980 Jun 1;29(11):1565-74. doi: 10.1016/0006-2952(80)90609-7.

Effect of modification of one histidine residue on the enzymatic and pharmacological properties of a toxic phospholipase A2 from Naja nigricollis snake venom and less toxic phospholipases A2 from Hemachatus haemachatus and Naja atra snake venoms.一个组氨酸残基的修饰对来自黑颈眼镜蛇蛇毒的有毒磷脂酶A2以及来自鼓腹咝蝰和中华眼镜蛇蛇毒的低毒磷脂酶A2的酶学和药理学特性的影响。

Toxicon. 1981;19(1):61-71. doi: 10.1016/0041-0101(81)90118-5.

Comparison of a relatively toxic phospholipase A2 from Naja nigricollis snake venom with that of a relatively non-toxic phospholipase A2 from Hemachatus haemachatus snake venom--I. Enzymatic activity on free and membrane bound substrates.黑颈眼镜蛇蛇毒中一种相对有毒的磷脂酶A2与拟眼镜蛇蛇毒中一种相对无毒的磷脂酶A2的比较——I. 对游离和膜结合底物的酶活性

Biochem Pharmacol. 1980 Jun 1;29(11):1555-63. doi: 10.1016/0006-2952(80)90608-5.

Effect of carboxylate group modification on enzymatic and cardiotoxic properties of snake venom phospholipases A2.羧基修饰对蛇毒磷脂酶A2酶活性和心脏毒性的影响

Toxicon. 1984;22(5):743-58. doi: 10.1016/0041-0101(84)90157-0.

The relationship between high-affinity noncatalytic binding of snake venom phospholipases A2 to brain synaptic plasma membranes and their central lethal potencies.蛇毒磷脂酶A2与脑突触质膜的高亲和力非催化结合与其中枢致死效力之间的关系。

Biochim Biophys Acta. 1986 Apr 25;856(3):457-70. doi: 10.1016/0005-2736(86)90137-9.

Inhibition of phosphorylation of rat synaptosomal proteins by snake venom phospholipase A2 neurotoxins (beta-bungarotoxin, notexin) and enzymes (Naja naja atra, Naja nigricollis).蛇毒磷脂酶A2神经毒素（β-银环蛇毒素、诺维毒素）和酶（眼镜蛇、黑颈眼镜蛇）对大鼠突触体蛋白磷酸化的抑制作用。

Toxicon. 1990;28(12):1423-37. doi: 10.1016/0041-0101(90)90156-2.

Chemical modification of the histidine residue in phospholipase A2 from the Hemachatus haemachatus snake venom.

Toxicon. 1980;18(5-6):529-47. doi: 10.1016/0041-0101(80)90081-1.

Effect of alkylation of tryptophan residues on the enzymatic and pharmacological properties of snake venom phospholipase A2.

Can J Physiol Pharmacol. 1985 Apr;63(4):331-9. doi: 10.1139/y85-060.

Comparative venomics and preclinical efficacy evaluation of a monospecific Hemachatus antivenom towards sub-Saharan Africa cobra venoms.比较毒液学和针对撒哈拉以南非洲眼镜蛇毒液的单特异性海蛇抗毒液的临床前疗效评价。

J Proteomics. 2021 May 30;240:104196. doi: 10.1016/j.jprot.2021.104196. Epub 2021 Mar 26.

Effects of beta-bungarotoxin and Naja naja atra snake venom phospholipase A2 on acetylcholine release and choline uptake in synaptosomes.β-银环蛇毒素和眼镜蛇蛇毒磷脂酶A2对突触体中乙酰胆碱释放和胆碱摄取的影响。

Toxicon. 1986;24(1):91-9. doi: 10.1016/0041-0101(86)90169-8.

引用本文的文献

Erythrocyte haemotoxicity profiling of snake venom toxins after nanofractionation.纳米分级后蛇毒毒素对红细胞的血液毒性分析。

J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Jun 30;1176:122586. doi: 10.1016/j.jchromb.2021.122586. Epub 2021 Feb 16.

Secreted Phospholipases A₂ from Animal Venoms in Pain and Analgesia.动物毒液中的分泌型磷脂酶 A₂与疼痛和镇痛。

Toxins (Basel). 2017 Dec 19;9(12):406. doi: 10.3390/toxins9120406.

Wound healing activity and mechanisms of action of an antibacterial protein from the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).东部菱斑响尾蛇（Crotalus adamanteus）毒液中一种抗菌蛋白的伤口愈合活性及作用机制

PLoS One. 2014 Feb 14;9(2):e80199. doi: 10.1371/journal.pone.0080199. eCollection 2014.

Crystallization and preliminary X-ray diffraction studies of BmooPLA2-I, a platelet-aggregation inhibitor and hypotensive phospholipase A2 from Bothrops moojeni venom.来自穆氏矛头蝮蛇毒液的血小板聚集抑制剂及降压磷脂酶A2——BmooPLA2-I的结晶与初步X射线衍射研究

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 1;67(Pt 8):900-2. doi: 10.1107/S174430911102392X. Epub 2011 Jul 19.

Studies on the status of lysine residues in phospholipase A2 from Naja naja atra (Taiwan cobra) snake venom.眼镜蛇（台湾眼镜蛇）蛇毒中磷脂酶A2赖氨酸残基状态的研究。

Biochem J. 1989 Sep 15;262(3):855-60. doi: 10.1042/bj2620855.

Properties of receptors for neurotoxic phospholipases A2 in different tissues.不同组织中神经毒性磷脂酶A2受体的特性

Neurochem Res. 1991 Jun;16(6):651-8. doi: 10.1007/BF00965551.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验