Pratt J H, Luft F C, Parkinson C A, Rankin L I
Steroids. 1981 Jan;37(1):1-6. doi: 10.1016/0039-128x(81)90002-7.
The effect of sodium intake on the aldosterone metabolic clearance rate (MCR) was examined in 5 normal subjects. Measurements were made under conditions where dietary sodium ranged from 10 to 1500 meq/day. There were no consistent changes in MCR over these extremes of sodium intake, and the plasma level of aldosterone correlated only with the aldosterone urinary excretion rate. In an additional group of 6 normal subjects, a single dose of 100 meq sodium administered orally had no effect on the aldosterone MCR. The findings indicate that aldosterone metabolism is unaffected by sodium intake.
在5名正常受试者中研究了钠摄入量对醛固酮代谢清除率（MCR）的影响。在饮食钠摄入量为10至1500毫当量/天的条件下进行测量。在这些钠摄入量的极端情况下，MCR没有一致的变化，并且醛固酮的血浆水平仅与醛固酮尿排泄率相关。在另外一组6名正常受试者中，口服单剂量100毫当量钠对醛固酮MCR没有影响。这些发现表明醛固酮代谢不受钠摄入量的影响。
