Svirbely J R, Speicher C E
Ther Drug Monit. 1980;2(3):211-6. doi: 10.1097/00007691-198007000-00002.
The interpretation of therapeutic drug monitoring data depends not only on the measurements themselves but also on additional data collected on the request forms and the manner in which the results are displayed on the report forms. A study was conducted to learn how presently used request/report forms affect the interpretation of therapeutic drug level measurements. Letters were sent to 232 directors of laboratory services requesting them to forward examples of forms that they use in therapeutic drug monitoring and toxicology. Replies were received from 77 directors of whom 53 enclosed examples of their therapeutic drug monitoring request/report forms. The characteristics of the 53 request/report forms were analyzed, and the results indicate that request/report forms are not optimally configured to facilitate effective therapeutic drug monitoring. Many request forms are not designed to allow entry of even the most basic data essential to the interpretation of therapeutic drug level measurements. Many report forms do little more than provide a drug level measurement and a therapeutic range. Improved request/report forms, as well as systems to ensure their proper use through adequate numbers of qualified personnel are necessary. Data/word processing computers should prove helpful.
治疗药物监测数据的解读不仅取决于测量本身，还取决于在申请表上收集的其他数据以及结果在报告单上的显示方式。开展了一项研究，以了解目前使用的申请/报告单如何影响治疗药物水平测量的解读。向232位实验室服务主任发送了信函，要求他们转发其在治疗药物监测和毒理学中使用的表格示例。收到了77位主任的回复，其中53位附上了他们的治疗药物监测申请/报告单示例。对这53份申请/报告单的特点进行了分析，结果表明申请/报告单的配置并非最佳，不利于有效的治疗药物监测。许多申请表甚至没有设计用于填写对治疗药物水平测量解读至关重要的最基本数据。许多报告单除了提供药物水平测量值和治疗范围外，几乎没有其他作用。需要改进申请/报告单，以及通过足够数量的合格人员确保其正确使用的系统。数据/文字处理计算机应会有所帮助。
