Calvert L J, Linder C W
J Fam Pract. 1978 Nov;7(5):953-6.
A case of suspected acetaminophen poisoning is reported in a child who ingested 19 gm of acetaminophen over a seven-day period. She exhibited evidence of severe renal and hepatic damage which resolved with supportive therapy. Serum levels of acetaminophen were not in the toxic range; hence, proof of the etiology was not possible. It is probable that a delay in suspecting acetaminophen toxicity allowed time for the serum acetaminophen level to return to normal. Acetaminophen is a safe drug when used properly, but overdosage can cause severe toxicity. With increased use in this country, increasing episodes of overdosages should be anticipated. Blood levels should be obtained early in acutely ill patients when acetaminophen toxicity is suspected.
据报道，一名儿童在七天内摄入了19克对乙酰氨基酚，疑似对乙酰氨基酚中毒。她出现了严重肾损伤和肝损伤的迹象，经支持治疗后症状缓解。对乙酰氨基酚的血清水平未处于中毒范围；因此，无法确定病因。很可能是怀疑对乙酰氨基酚中毒的时间延迟，使得血清对乙酰氨基酚水平恢复正常。对乙酰氨基酚在正确使用时是一种安全的药物，但过量服用会导致严重毒性。随着该国对乙酰氨基酚使用量的增加，预计过量服用的情况会增多。当怀疑急性病患者出现对乙酰氨基酚中毒时，应尽早检测血药浓度。
