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[流感病毒感染中的免疫学方法(作者译)]

[Immunological methods in influenzavirus-infections (author's transl)].

作者信息

Luther P, Weber S, Pohl W D, Noack K, Possner S, Bergmann K C

出版信息

Z Erkr Atmungsorgane. 1981;156(1):22-8.

PMID:7222804
Abstract

Immunological methods for detection of specific antibodies after viral infections are described. The counterimmunoelectrophoresis detects various precipitating antibodies in serum and sputum (against organic dusts, p.e. bird proteins, aspergillus and viral antigens) and is suitable for routine-work due to its sensitivity and simplicity. The sepharose-fluorescence-test is very sensitive and only small quantities of test reagents are required (detection of IgA-, -M, -G-antibodies). The LN-Test (lectin-neuraminidase-test) is well suitable to detect virus-neuraminidase activities as well as antibodies against neuraminidase in human sera.

摘要

本文描述了病毒感染后检测特异性抗体的免疫学方法。对流免疫电泳可检测血清和痰液中的各种沉淀抗体(针对有机粉尘,如鸟类蛋白、曲霉菌和病毒抗原),因其灵敏度和简便性适用于常规工作。琼脂糖荧光试验非常灵敏,仅需少量检测试剂(检测IgA、IgM、IgG抗体)。LN试验(凝集素-神经氨酸酶试验)非常适合检测人血清中的病毒神经氨酸酶活性以及抗神经氨酸酶抗体。

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