Jacobasch K H
Z Gesamte Inn Med. 1981 Jan 15;36(2):suppl 214-7.
Incidence and mortality of the carcinoma of the large intestine increase also in the GDR. Carcinomas mostly develop in adenomas of the large intestine in the course of several years. Nowadays the adenoma-carcinoma-sequence is regarded as ascertained. The environmental influences are of decisive importance for the genesis of the colon carcinoma. Apart from this also genetic factors play a part. Villous adenomas more frequently show malignant structures than tubular adenomas. In large adenomas with a diameter of more than 20 mm more frequently invasive carcinomas (20-40%) are found than in small adenomas with a diameter of less than 10 mm (1%). From this is to be derived the demand of the removal of all adenomas of the large intestine with a diameter larger than 5 mm. The method of choice of the treatment is the polypectomy and the technique with the diathermy loop.
在民主德国，大肠癌的发病率和死亡率也有所上升。癌大多在数年的病程中发生于大肠腺瘤。如今，腺瘤 - 癌序列被认为是确定的。环境因素对结肠癌的发生具有决定性意义。除此之外，遗传因素也起作用。绒毛状腺瘤比管状腺瘤更常出现恶性结构。直径大于20毫米的大腺瘤比直径小于10毫米的小腺瘤更常发现浸润性癌（20 - 40%对比1%）。由此得出需要切除所有直径大于5毫米的大肠腺瘤。治疗的首选方法是息肉切除术以及使用电凝圈套器的技术。
