Lutze G, Schlote A, Urbahn H
Z Gesamte Inn Med. 1981 Feb 15;36(4):102-6.
In in-vivo- and in-vitro-examinations the activated recalcification time, the recalcification time of the plasma, the partial thromboplastin time and the thrombin time were compared concerning their suitability for the control of a heparin therapy. The laboratory methods tested considerably differed in their sensitivity compared with heparin and in the possibility of a quantitative statement. The use of a certain laboratory method depends on the indication for a heparin therapy and on the heparin concentration in the blood to be expected. While thrombin time, recalcification time of the plasma and the partial thromboplastin time are suited only for the proof of lower heparin concentrations, the activated recalcification time allows also the proof of higher heparin concentrations in the blood.
在体内和体外检查中，比较了活化复钙时间、血浆复钙时间、部分凝血活酶时间和凝血酶时间对肝素治疗控制的适用性。与肝素相比，所测试的实验室方法在敏感性和定量表述可能性方面有很大差异。某种实验室方法的使用取决于肝素治疗的指征以及预期血液中的肝素浓度。虽然凝血酶时间、血浆复钙时间和部分凝血活酶时间仅适用于低肝素浓度的检测，但活化复钙时间也可用于检测血液中较高的肝素浓度。
